The aim of this study was to define the interrelationship between electrogastrogram(EGG) and intragastric pressure(IGP), and the effect of gastric pacing on gastric contraction. Direct EGG was recorded with serosal electrodes positioned along the
greater curvature of the stomach and indirect EGG with cutaneous electrodes on the upper abdominal skin. Changes of IGP were recorded by means of pressure transducer with balloon catheter in the distal gastric cavity.
The basal gastric electrical activity(GEA) was generated in the fundus at a mean frequency of 5.1±0.1 cpm and was propagated aborad. Meanfrequency of GEA was reduced to 3.4±0.1 cpm under sodium pentobarbital anesthesia. Frequencies of GEA and
IGP
change were similar, and IGP was increased with increasing of GEA amplitude. After bilateral cervical vagotomies amplitudes of GEN and IGP were decreased, but they were increased by electrical stimulation of distal vagus nerve at 1 V, 1 ms, and
20
Hz.
Frequency of IGP change was increased by electrical stimulation of gastric fundus at 10 V, 50 ms, and 4~5 cpm, but amplitude was not. Amplitude of IGP change was increased by electrical stimulation of gastric fundus at 5 V, 50 ms, and 20~30 cpm,
but
frequency was not.
In conlusion, frequency and amplitude of IGP change chan be changed by various electrical stimulation of distal vagal nerve after vagotomies and of gastric fundus.
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